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Q&A: Daniel M. Blumenthal, MD, MBA Substance Abuse And Cardiovascular Disease

Interviewed by Mark Gold, MD FEATURED ADDICTION EXPERT: Daniel M. Blumenthal, MD, MBA Attending Physician, Division of Cardiology, Massachusetts General Hospital Instructor of Medicine at Harvard Medical School Associate Chief Medical Officer at Devoted Health Do FDA-approved psychostimulants increase the risk of cardiovascular events? There is no convincing evidence that FDA-approved psychostimulants (e.g. methylphenidate, dextroamphetamine, […]

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Smart Approaches To Marijuana Issues Comprehensive Rebuttal To New York State Report Recommending Marijuana Legalization

Group formally submits Freedom of Information Law (FOIL) request to obtain sources that contributed to the creation of the New York State report released by the Department of Health endorsing legalization (New York, New York) – Today, Smart Approaches to Marijuana (SAM), in coordination with its award-winning science advisory board and its New York State […]

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Brian Boyd: HSE Giving Out The Wrong Line About Cocaine

Safety campaign should tell middle classes moral truth about dangerous grubby drug I’m sure the good people at the Health Service Executive were trying to be all mature and socially relevant about Ireland’s growing cocaine problem when they issued their “harm reduction” guidelines recently on how to make taking the drug safer. But they weren’t. […]

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Cancer-Causing Compounds Found In Cannabis Oil

As the legalization of marijuana continues to spread among various states within the U.S., researchers, and physicians are trying to fully grasp the potential health hazards of the recreational use of the drug. Since marijuana can be consumed through a variety of methods—e.g., eating, smoking, or vaporizing—it is important to understand if and how drug delivery […]

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Long-Term Use Of Cannabis Or Medication Derived From The Drug Impairs Memory, Conclude Researchers

Trials on mice showed those exposed to cannabinoids had memory impairments Brain scans by British and Portuguese researchers then confirmed the finding The new experiment shines a light on the little-known dangers of cannabinoids Smoking cannabis or taking medication based on the drug can harm the brain and damage memory, research has found. Trials on mice […]

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Systematic Review And Meta-analysis Of Cannabinoids In Palliative Medicine

Authors: Mücke M, Weier M, Carter C, Copeland J, Degenhardt L, Cuhls H, Radbruch L, Häuser W, Conrad R. Abstract We provide a systematic review and meta-analysis on the efficacy, tolerability, and safety of cannabinoids in palliative medicine. The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PsycINFO, PubMed, Scopus, and http://clinicaltrials.gov, and a selection of cancer journals were searched up until 15th […]

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Cannabis’ Effects On Diabetes Unclear

Cannabis’ effects on diabetes unclear – by Dr. Elizabeth Ko & Dr. Eve Glazier – Ask the Doctors  column, August 4, 2018 –  Ask the Doctors, c/0 Media Relations, UCLA Health, 924 Westwood Blvd. Suite 350, Los Angeles, CA  90095 Question:  I have Type 1 diabetes and have used marijuana for years to control my […]

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Common Marijuana-related Cases Encountered In The Emergency Department

In 2000, Colorado voters decriminalized marijuana for medical use; however, because marijuana use remained illegal under federal law, the number of users was low. In 2009, President Obama instructed federal officials not to enforce marijuana laws that were in conflict with state laws, and the number of registered medical marijuana users in Colorado increased to 60,000 […]

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More Than Half Of New Yorkers Oppose Marijuana Legalization, According To New Emerson College Poll

More Than Three Quarters of African-American and Latino Respondents Did Not Support Marijuana Legalization Today, Smart Approaches to Marijuana (SAM) and its New York Affiliate, SAM-NY, released the results of a new Emerson College poll finding that the majority of New Yorkers do not support the legalization of marijuana. A plurality support either decriminalization or the […]

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5 Steps To Marijuana Legalization

This week’s stories inadvertently illustrate the step-by-step process proponents employ to legalize marijuana for medical and recreational use. Step 1. Target states with ballot initiatives. Tell voters patients need marijuana for medical use, despite a lack of supporting evidence. Deny evidence that the drug is addictive, harmful to the developing brain, and is associated with […]

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America’s Invisible Pot Addicts

The proliferation of retail boutiques in California did not really bother him, Evan told me, but the billboards did. Advertisements for delivery, advertisements promoting the substance for relaxation, for fun, for health. “Shop. It’s legal.” “Hello marijuana, goodbye hangover.” “It’s not a trigger,” he told me. “But it is in your face.” When we spoke, […]

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Amid Opioid Crisis, Texas Subsidized Drug Distributor It’s Now Investigating

In 2016, Gov. Greg Abbott announced a $9.75 million grant to McKesson Corporation. Now, Texas is among the states investigating the giant drug distributor’s role in a growing opioid crisis In the early months of 2016, as U.S. overdose deaths were on track to break records and the number of Texas infants born addicted to […]

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Fentanyl Use Drove Drug Overdose Deaths To A Record High In 2017, CDC Estimates

By Christopher Ingraham Drug overdose deaths surpassed 72,000 in 2017, according to provisional estimates recently released by the Centers for Disease Control and Prevention. That represents an increase of more than 6,000 deaths, or 9.5 percent, over the estimate for the previous 12-month period. That staggering sum works out to about 200 drug overdose deaths every single day, […]

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Overdose Crisis? Or, Addiction Crisis?

By Jason Schwartz British Columbia has long been cited as a model for North American drug policy and harm reduction implementation. BC has established a Death Review Panel in response to the overdose crisis. The panel recently issued a report with 3 recommendations. The first recommendation to regulate recovery homes, which currently require only a simple inspection of the […]

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Known Cannabis Teratogenicity Needs To Be Carefully Considered

It is no accident that in almost the same week both Australia and UK have decided that cannabis is to be recommended for a host of medical disorders mostly in advance of gold standard clinical trials. This is a direct product of the organized transnational global drug liberalization movement orchestrated from New York. I wish […]

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Incidence Of Gastroschisis In California

  Source: https://jamanetwork.com/journals/jamasurgery/article-abstract/2689028

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Childhood Adversity Increases Susceptibility To Addiction Via Immune Response

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body’s immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome “La Sapienza,” Italy. The study, published in Biological Psychiatry, showed that exposure to psychosocial stress early in life altered the […]

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Endocannabinoid Signaling In Social Functioning: An RDoC Perspective

Abstract Core deficits in social functioning are associated with various neuropsychiatric and neurodevelopmental disorders, yet biomarker identification and the development of effective pharmacological interventions has been limited. Recent data suggest the intriguing possibility that endogenous cannabinoids, a class of lipid neuromodulators generally implicated in the regulation of neurotransmitter release, may contribute to species-typical social functioning. […]

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Endocannabinoid Mediates Excitatory Synaptic Function of β-Neurexins. Commentary: β-Neurexins Control Neural Circuits By Regulating Synaptic Endocannabinoid Signaling

Introduction Synaptic cell-adhesion molecules and their interactions with other molecular pathways affect both synapse formation and its function (Varoqueaux et al., 2006; Sudhof, 2008; Bemben et al., 2015a). Neurexins are presynaptic cell-adhesion molecules that interact with neuroligins and other postsynaptic partners. Neurexins are encoded by three genes, each of which encodes a long and short isoform, termed […]

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β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling

Abstract α- and β-neurexins are presynaptic cell-adhesion molecules implicated in autism and schizophrenia. We find that although β-neurexins are expressed at much lower levels than α-neurexins, conditional knockout of β-neurexins with continued expression of α-neurexins dramatically decreased neurotransmitter release at excitatory synapses in cultured cortical neurons. The β-neurexin knockout phenotype was attenuated by CB1-receptor inhibition […]

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Class A drug use among young people highest in a decade as price of cocaine falls

A fall in the price of cocaine has led to the highest number of young people using class A drugs in more than a decade, experts say. Cocaine prices are at their lowest levels in more than 25 years and young people are finding Class A drugs easily accessible, charities warned.  The drug is more widely […]

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Some video results of legalisation of marijuana in USA

These are very shocking videos with information about some of the effects of drug legalisation in the USA.    

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CB1R Expression Key to Understanding Cannabis Teratology

  In an era when 24% of teenage Californian mothers test cannabis-positive it is unfortunate that the vast and conflicting literature on cannabis teratology has created professional confusion on the important subject of cannabis teratology.  An appreciation of overarching patterns can contribute to clarity in this field. There is considerable agreement in the literature that […]

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Temporal Associations of Alcohol and Tobacco Consumption With Cancer Mortality

  Key Points Question  Are changes in population-level alcohol and tobacco consumption associated with changes in overall cancer mortality? Findings  In this population-based cohort study, temporal associations of alcohol and tobacco consumption with cancer mortality overall were found using Australian time series data (1935-2014). An estimated 1-L decrease in alcohol consumption per capita and a 1-kg decrease […]

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New Study Finds Marijuana Legalization Will Cost Illnois $670.5 Million Per Year

Report by prominent marijuana policy group finds costs would outweigh any tax revenue under legalization; Healthy and Productive Illinois coalition urges rejection of legalization Today, the day before the unofficial “marijuana holiday,” Healthy and Productive Illinois (HPIL) – a project of Smart Approaches to Marijuana Action (SAM Action) – released a comprehensive working paper on the projected costs of legalization in […]

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An Update On Safety And Side Effects Of Cannabidiol: A Review Of Clinical Data And Relevant Animal Studies

by Kerstin Iffland and Franjo Grotenhermen Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from updating the literature, this article focuses on clinical studies and CBD potential interactions with other drugs. Results: In general, the often described favorable safety profile of CBD […]

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Scientists Pinpoint Brain Region That May Be Center Of Alcohol Addiction

Researchers map out a cellular mechanism that offers a biological explanation for alcoholism, and could lead to treatments Credit: Getty Images You can lead a lab rat to sugar water, but you can’t make him drink—especially if there’s booze around. New research published Thursday in Science may offer insights into why some humans who drink alcohol develop an […]

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Marijuana Industry Loses Key Protection From Federal Enforcement In Proposed Spending Bill

There was big news in Congress today that I wanted you to know about. A proposed government spending bill released today eliminated a provision that has protected the marijuana industry from federal prosecution for violating the Controlled Substances Act. The Rohrabacher-Farr language was eliminated from the Commerce, Justice, Science bill that funds the Department of […]

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Another Hurdle Cleared – Marijuana Industry Fails In The House

There was big news in Congress yesterday that I wanted you to know about. We are pleased to report that the House has not included any pro-pot riders in its spending bills this year! Thank you for all of your efforts, including calls and emails. Congress has heard your voice and acted to preserve the […]

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Report by National Families in Action Rips the Veil Off the Medical Marijuana Industry

TO ALL OUR READERS: THE NDPA WOULD URGE YOU TO READ THE REPORT MENTIONED IN THE ARTICLE BELOW, (Tracking the Money That’s Legalizing Marijuana and Why It Matters), WHICH GIVES A DETAILED DESCRIPTION OF HOW MARIJUANA BECAME THE NUMBER ONE DRUG OF CHOICE FOR MILLIONS OF PEOPLE WORLDWIDE, HOW IT BECAME ‘BIG BUSINESS’ IN THE […]

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"When representing a cause (almost) lost, sound your trumpet, mount your steed and go for the very last charge, failing which you will die of sad old age in the depths of the forgotten fortress, no longer besieged because life has abandoned it for greener pastures."

Jean Raspail
From the website of jeanraspail.net

"Universal prevention initiatives are important elements of a comprehensive prevention strategy that should include selective and indicated prevention initiatives as well. In order to prevent the development of dependence you need all three - and you cannot do without universal prevention. Norms, attitudes, availability are important risk factors for developing drug use problems as well as neighbourhood disorganization and weak family bonds."

Christina Gynna, Deputy National Drugs Policy Co-ordinator, Sweden,
at the ICAA conference in Budapest, 24 October 2005

 
 

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