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Known Cannabis Teratogenicity Needs To Be Carefully Considered

It is no accident that in almost the same week both Australia and UK have decided that cannabis is to be recommended for a host of medical disorders mostly in advance of gold standard clinical trials. This is a direct product of the organized transnational global drug liberalization movement orchestrated from New York. I wish […]

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Incidence Of Gastroschisis In California

  Source: https://jamanetwork.com/journals/jamasurgery/article-abstract/2689028

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Childhood Adversity Increases Susceptibility To Addiction Via Immune Response

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body’s immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome “La Sapienza,” Italy. The study, published in Biological Psychiatry, showed that exposure to psychosocial stress early in life altered the […]

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Endocannabinoid Signaling In Social Functioning: An RDoC Perspective

Abstract Core deficits in social functioning are associated with various neuropsychiatric and neurodevelopmental disorders, yet biomarker identification and the development of effective pharmacological interventions has been limited. Recent data suggest the intriguing possibility that endogenous cannabinoids, a class of lipid neuromodulators generally implicated in the regulation of neurotransmitter release, may contribute to species-typical social functioning. […]

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Endocannabinoid Mediates Excitatory Synaptic Function of β-Neurexins. Commentary: β-Neurexins Control Neural Circuits By Regulating Synaptic Endocannabinoid Signaling

Introduction Synaptic cell-adhesion molecules and their interactions with other molecular pathways affect both synapse formation and its function (Varoqueaux et al., 2006; Sudhof, 2008; Bemben et al., 2015a). Neurexins are presynaptic cell-adhesion molecules that interact with neuroligins and other postsynaptic partners. Neurexins are encoded by three genes, each of which encodes a long and short isoform, termed […]

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β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling

Abstract α- and β-neurexins are presynaptic cell-adhesion molecules implicated in autism and schizophrenia. We find that although β-neurexins are expressed at much lower levels than α-neurexins, conditional knockout of β-neurexins with continued expression of α-neurexins dramatically decreased neurotransmitter release at excitatory synapses in cultured cortical neurons. The β-neurexin knockout phenotype was attenuated by CB1-receptor inhibition […]

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Class A drug use among young people highest in a decade as price of cocaine falls

A fall in the price of cocaine has led to the highest number of young people using class A drugs in more than a decade, experts say. Cocaine prices are at their lowest levels in more than 25 years and young people are finding Class A drugs easily accessible, charities warned.  The drug is more widely […]

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Some video results of legalisation of marijuana in USA

These are very shocking videos with information about some of the effects of drug legalisation in the USA.    

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CB1R Expression Key to Understanding Cannabis Teratology

  In an era when 24% of teenage Californian mothers test cannabis-positive it is unfortunate that the vast and conflicting literature on cannabis teratology has created professional confusion on the important subject of cannabis teratology.  An appreciation of overarching patterns can contribute to clarity in this field. There is considerable agreement in the literature that […]

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Temporal Associations of Alcohol and Tobacco Consumption With Cancer Mortality

  Key Points Question  Are changes in population-level alcohol and tobacco consumption associated with changes in overall cancer mortality? Findings  In this population-based cohort study, temporal associations of alcohol and tobacco consumption with cancer mortality overall were found using Australian time series data (1935-2014). An estimated 1-L decrease in alcohol consumption per capita and a 1-kg decrease […]

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New Study Finds Marijuana Legalization Will Cost Illnois $670.5 Million Per Year

Report by prominent marijuana policy group finds costs would outweigh any tax revenue under legalization; Healthy and Productive Illinois coalition urges rejection of legalization Today, the day before the unofficial “marijuana holiday,” Healthy and Productive Illinois (HPIL) – a project of Smart Approaches to Marijuana Action (SAM Action) – released a comprehensive working paper on the projected costs of legalization in […]

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An Update On Safety And Side Effects Of Cannabidiol: A Review Of Clinical Data And Relevant Animal Studies

by Kerstin Iffland and Franjo Grotenhermen Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from updating the literature, this article focuses on clinical studies and CBD potential interactions with other drugs. Results: In general, the often described favorable safety profile of CBD […]

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Scientists Pinpoint Brain Region That May Be Center Of Alcohol Addiction

Researchers map out a cellular mechanism that offers a biological explanation for alcoholism, and could lead to treatments Credit: Getty Images You can lead a lab rat to sugar water, but you can’t make him drink—especially if there’s booze around. New research published Thursday in Science may offer insights into why some humans who drink alcohol develop an […]

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Marijuana Industry Loses Key Protection From Federal Enforcement In Proposed Spending Bill

There was big news in Congress today that I wanted you to know about. A proposed government spending bill released today eliminated a provision that has protected the marijuana industry from federal prosecution for violating the Controlled Substances Act. The Rohrabacher-Farr language was eliminated from the Commerce, Justice, Science bill that funds the Department of […]

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Another Hurdle Cleared – Marijuana Industry Fails In The House

There was big news in Congress yesterday that I wanted you to know about. We are pleased to report that the House has not included any pro-pot riders in its spending bills this year! Thank you for all of your efforts, including calls and emails. Congress has heard your voice and acted to preserve the […]

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The Opioid Crisis Ravaging America Is Claiming Record Numbers Of Lives

The opioid crisis is unlike any drug epidemic America has ever known. It’s claiming lives at an almost unimaginable rate. But to get an idea of why these drugs are taking such a toll, you have to look at the people who are dying. This is not just the curse of the stereotypical addict. Many […]

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An Unexpected Pathway From Cannabidiol To Genotoxicity – PPARγ: CBD To GENOTOX!!!

I was just learning this morning that CBD is well documented to trigger and act via PPAR gamma receptors which are well known to physicians as used in a class of diabetes drugs called the thiazolidinediones (pioglitazone and its congeners). So I thought I should just check if this was involved in pregnancy and gestation. […]

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Changes Already Occurring In Oregon After Recreational Legalization

The Oregon Health Authority also issued this month a baseline report titled Marijuana Report: Use, Attitudes, and Health Effects in Oregon. This comprehensive report includes several key findings.   Pictured above, for example, is a state map showing the 40 cities and 11 counties that have banned marijuana businesses within their boundaries. However, the Oregon Medical […]

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In Oregon, 22 Doctors Are Responsible For 85% Of Medical Marijuana Recommendations

The Oregon Health Authority has issued two new reports on marijuana. Oregon’s Medical Marijuana Program: Statistical Snapshot, January 2016 finds that 22 physicians have recommended marijuana for medical use to 85% of the state’s registered patients.   Some 1,700 physicians serve between 1 and 449 patients and account for a total of 19,087 patients, while […]

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Cannabis oil: what is it and does it really work as medicine?

Cannabis oil has come under scrutiny RUNGROJ YONGRIT/EPA-EFE/REX/Shutterstock By Alison George Cannabis is in the headlines for its potential medical benefits after the recent confiscation of cannabis oil medication from the mother of a 12-year-old British boy with severe epilepsy. The furore that ensued is shining a light on campaigns for cannabis oils to be made legal for […]

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Powerful Documentary On The Impact Of Marijuana In The Brain

Watch Here and Share! As the legal status of marijuana changes its perceived dangers are lessening while the potency of the drug is increasing. This video covers marijuana as a psychoactive substance that induces its effects by manipulation of natural brain chemicals known as  the endocannabinoids.The toxic and addictive impact that results from the drug’s disruption of natural […]

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Report by National Families in Action Rips the Veil Off the Medical Marijuana Industry

TO ALL OUR READERS: THE NDPA WOULD URGE YOU TO READ THE REPORT MENTIONED IN THE ARTICLE BELOW, (Tracking the Money That’s Legalizing Marijuana and Why It Matters), WHICH GIVES A DETAILED DESCRIPTION OF HOW MARIJUANA BECAME THE NUMBER ONE DRUG OF CHOICE FOR MILLIONS OF PEOPLE WORLDWIDE, HOW IT BECAME ‘BIG BUSINESS’ IN THE […]

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Children As Young As 12 Taking Drugs In West Belfast Says New Report

There will never be fundamental change in west Belfast’s drug problem without addressing the poverty and conflict legacies affecting it, a new report has found. Launched on Monday, the West Belfast Community Drugs Panel’s report examined all aspects of drugs misuse in the area and provided a series of recommendations. The panel was set up […]

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The Role Of Families In Effective Prevention Programmes

Submitted by Livia Edegger Strengthening Families Programme, a family-focused prevention programme used in 26 countries around the world, was found to be nine times more effective than individually-targeted programmes and yielded a $10 return for every dollar spent on it. The programme, designed for youth and their families, aims to improve parent-child interactions, parenting skills and […]

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Even Casual Cannabis Use Can Affect Health

Submitted by Livia Edegger  As support for decriminalising and legalising marijuana is growing, several new studies highlight the potentially harmful effects of the drug on its user’s brain and heart. The findings are particularly revealing in the field of recreational cannabis use. While studying the brains of a group of twenty occasional cannabis smokers, researchers from […]

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Adults Who Initiate Alcohol And Marijuana Use Before The Age Of 21 Are Much More Likely To Abuse Or Become Dependent In Later Years

Submitted by Andy Travis  Early onset of alcohol use is associated with a greater likelihood of developing alcohol abuse or dependence at a later age, according to data from the US National Survey on Drug Use and Health (NSDUH). Those who first used alcohol at or before the age of 14 were nearly four times more […]

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International Outcry Grows Over Alcohol Industry Role In Policy Making

Submitted by Andy Travis This forthright editorial in the journal ‘Addiction’ joins over 500 public health leaders and 27 organisations in questioning the role of the global alcohol industry in making alcohol policy. Conflict with the tobacco industry is well documented, where vested interests have fought an aggressive rearguard action against efforts to reduce tobacco harm. […]

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Drug Free Workplace Policies

An effective drug-free workplace policy is one of the best ways for employers to protect their businesses. An effective program does not end with pre-employment screening, since any drug user can count up to three days before the test and then begin to use again after being hired. Drug-free workplace policies reduce the amount of […]

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Video Of Connor Reid Eckhardt

This is a very powerful and heartbreaking story –  let us hope many young people will take notice and never ‘try’ drugs offered by ‘a friend’ Connor Reid Eckhardt added a new video. “THIS IS SO IMPORTANT TO SHARE….THIS IS NOT A MOVIE!! OUR 19 YEAR OLD SON CONNOR IS NOT WAKING UP FROM THE SINGLE HIT […]

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Over 400 Conditions Co-occur With Fetal Alcohol Spectrum Disorders (FASD), Study Finds

Researchers at the Centre for Addiction and Mental Health (CAMH) have identified 428 distinct disease conditions that co-occur in people with Fetal Alcohol Spectrum Disorders (FASD), in the most comprehensive review of its kind. The results were published today in The Lancet. “We’ve systematically identified numerous disease conditions co-occurring with FASD, which underscores the fact that […]

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JOURNAL PRINTS CORRECTION: MARIJUANA USE LINKED WITH 2.5-FOLD INCREASE IN PSYCHOSIS

Psychology of Addictive Behaviors journal makes corrections, SAM calls on media to correct stories FOR IMMEDIATE RELEASE January 19, 2015 Contact: Jeffrey Zinsmeister jeff@learnaboutsam.org +1 (415) 680-3993 [WASHINGTON, DC] – A prominent journal article about marijuana and health which resulted in media outlets reporting on marijuana’s harmlessness has now been corrected. A recheck of the statistics […]

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Prevention Measures Lower Prescription Drug Abuse In US

Submitted by Livia Edegger  US researchers that analysed over a million lab samples found that prescription drug abuse is twice as likely to decrease in states with drug prevention programmes in place. The states of Florida, Georgia, Kentucky, New York and Tennessee have seen a decline of 10% in prescription drug abuse, a rate 2.5 higher […]

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Germany Releases Drug Report

Submitted by Livia Edegger Earlier this month Germany celebrated the results of the 2014 drug report which revealed a rapid decline in smoking, drinking and marijuana use among youth over the past ten years. Smoking among German teens aged 12 – 17 has halved in ten years (11.7%). Smoking rates have also dropped among 18 – […]

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Early Onset Of Drug Use Linked To Mental Disorders And Multi-drug Use

Submitted by Livia Edegger A study conducted by the US Substance Abuse and Mental Health Services Administration (SAMHSA) found that individuals who had started taking drugs early on in life were more likely to develop mental disorders and become polydrug users. At the time of clinical admission, three quarters of drug users between 18 and 30 […]

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Drug use plunges 50% among secondary school students in England

Submitted by Livia Edegger The findings of a report released by the Health and Social Care Information Centre (HSCIC) reveal a promising downward trend regarding drug use among secondary school students in England. Tobacco, alcohol and drug use among students have been cut in half in the past ten years. Smoking rates have dropped from 9% […]

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Teenage Rugby Player Cut Off Penis While High On Skunk, Says Father Who Wants Drug Made Class A 

A teenage rugby player cut off his own penis and stabbed his mother while high on skunk, his father has revealed, as he called for the drug to be reclassified. The father, named only as Nick because he wants to remain anonymous as his son is rebuilding his life, is backing Lord Nicholas Monson’s campaign to […]

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University Of Florida Drug Policy Institute Joins Senior Researchers At Harvard, Boston Children’s Hospital, University Of Texas, And Others In Responding To Latest Claims By The International Centre For Science In Drug Policy

A team of researchers from the UF Drug Policy Institute, Harvard University, and other institutions authored a lengthy response to a recent monograph written by the George Soros-funded ICSDP claiming that cannabis health claims have been overblown. The team, led by former American Society of Addiction Medicine President Stu Gitlow, and other researchers with leadership ties to groups […]

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Here Are The Countries That Smoke The Most Marijuana

Just finished reading the cannabis section of the world drug report mentioned below and here were of the points that stuck out to me: Cannabis herb (they make a distinction between herb and resin) seizures in North America account for 64% of worldwide seizures. US outdoor eradication rates significantly dropped (6,470 in 2012 from 23, […]

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"When representing a cause (almost) lost, sound your trumpet, mount your steed and go for the very last charge, failing which you will die of sad old age in the depths of the forgotten fortress, no longer besieged because life has abandoned it for greener pastures."

Jean Raspail
From the website of jeanraspail.net

"Universal prevention initiatives are important elements of a comprehensive prevention strategy that should include selective and indicated prevention initiatives as well. In order to prevent the development of dependence you need all three - and you cannot do without universal prevention. Norms, attitudes, availability are important risk factors for developing drug use problems as well as neighbourhood disorganization and weak family bonds."

Christina Gynna, Deputy National Drugs Policy Co-ordinator, Sweden,
at the ICAA conference in Budapest, 24 October 2005

 
 

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