Child abuse can lead to substance abuse

Carl Anderson, a Harvard instructor in psychiatry and a research associate in McLean Hospitals Developmental Biopsychiatry Research Laboratory and Brain Imaging Center, and his colleagues found that repeated sexual abuse affects the blood flow and function of a key brain region related to substance abuse, the cerebellar vermis. This part of the brain has been recently implicated in the coordination of emotional behavior, is strongly affected by alcohol, cocaine, and other drugs of abuse, and may help regulate dopamine, a neurotransmitter critically involved in addiction.
‘Damage to this area of the brain may cause an individual to be particularly irritable, and to seek external means, such as drugs or alcohol, to quell this irritability,” said Anderson.
Anderson said the teams findings enhance understanding of the developmental mechanisms of childhood sexual abuse, which may result in new methods of treatment for child-abuse survivors.