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OPERATION PREVENTION – VIDEO CHALLENGE

Teenagers across America were invited to submit 30-60 second video public service announcements that capture their unique voice in order to communicate the opioid epidemic as a national crisis. The second-annual video challenge is a part of a joint nationwide education initiative titled Operation Prevention that educates students about the science behind addiction and its […]

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Epidemiological Overview Of Multidimensional Chromosomal And Genome Toxicity Of Cannabis Exposure In Congenital Anomalies And Cancer Development

Cannabis and cannabinoids are implicated in multiple genotoxic, epigenotoxic and chromosomal-toxic mechanisms and interact with several morphogenic pathways, likely underpinning previous reports of links between cannabis and congenital anomalies and heritable tumours. However the effects of cannabinoid genotoxicity have not been assessed on whole populations and formal consideration of effects as a broadly acting genotoxin […]

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What Is Kratom? Users Praise Its Pain-Relieving Ability, But Louisiana Officials Look To Ban It

Kratom, in powder form, can be taken in capsules or brewed into a tea. A kratom leaf, the source of an herbal supplement that users say can provide pain relief and relieve insomnia, among other uses. Vivian Allen sought chronic pain relief. A car wreck left the 55-year-old grandmother immobilized. Six subsequent back surgeries led […]

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Cannabis Regulations Inadequate Given Rising Health Risks Of High-Potency Products

Nearly half of all U.S. citizens now live in a state where they can purchase cannabis from a recreational market, and all but 13 states have legalized medical use.  These state-level policies have all been developed and adopted under a federal prohibition, which may be changing soon as lawmakers in both the House and the […]

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Association Between Cannabis Use Disorder And Schizophrenia Stronger In Young Males Than In Females

Abstract Background Previous research suggests an increase in schizophrenia population attributable risk fraction (PARF) for cannabis use disorder (CUD). However, sex and age variations in CUD and schizophrenia suggest the importance of examining differences in PARFs in sex and age subgroups. Methods We conducted a nationwide Danish register-based cohort study including all individuals aged 16–49 […]

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Marijuana Know The Truth Hits Illinois

Drug Free America Foundation is launching its new digital advertisement campaign targeting viewers in Illinois. The digital animated ad is the second in a series titled “Marijuana…Know the Truth” and discusses the real dangers of marijuana use.   As you know, Illinois is a state that is considering legalizing recreational marijuana this year. We hope this […]

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Depressive Symptoms, Mental Wellbeing, And Substance Use Among Adolescents Before And During The COVID-19 Pandemic In Iceland: A Longitudinal, Population-based Study

Summary Background Adolescence represents a crucial developmental period in shaping mental health trajectories. In this study, we investigated the effect of the COVID-19 pandemic on mental health and substance use during this sensitive developmental stage. Methods In this longitudinal, population-based study, surveys were administered to a nationwide sample of 13–18-year-olds in Iceland in October or […]

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Pilot Study Shows: Every Five Minutes, Young People Are Reminded Of Alcohol With Incentives

A pilot study by Addiction Switzerland traced the alcohol incentives on the routes of 16 to 19-year-old adolescents in everyday life and in social networks. On average, the test subjects in the five largest Swiss cities encountered an alcohol incentive every five minutes. Alcohol was also omnipresent in social networks, transported by friends and influencers, who are […]

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Alcohol Consumption And MRI Markers Of Brain Structure And Function: Cohort Study Of 25,378 UK Biobank Participants

Highlights Alcohol intake is associated with smaller grey matter volumes across the brain. It is also associated with lower FA and increased functional connectivity Binge drinking steepens association between alcohol and total grey matter volume. Findings suggest even 7–14 units of alcohol weekly may be associated with brain differences. Abstract Moderate alcohol consumption is widespread but its […]

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What The Aaron Hernandez Documentary Missed About His Brain

  Aaron Hernandez was supposed to be the epitome of the American Dream—overcoming childhood setbacks to earn a spot in the NFL on the New England Patriots. Millions of kids across America wish they could be so lucky. But the 2020 documentary on Netflix, “Killer Inside: The Mind of Aaron Hernandez,” takes a deep dive […]

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Contemporary Epidemiology Of Rising Atrial Septal Defect Trends Across USA 1991–2016: A Combined Ecological Geospatio/Temporal And Causal Inferential Study

Abstract Background: Cardiovascular anomalies are the largest group of congenital anomalies and the major cause of death in young children, with various data linking rising atrial septal defect incidence (ASDI) with prenatal cannabis exposure. Objectives / Hypotheses: Is cannabis associated with ASDI in USA? Is this relationship causal? Methods: Geospatio/temporal cohort study, 1991–2016. Census populations […]

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Using Neuroscience To Prevent Drug Addiction Among Teenagers

One way to deter harmful recreational drug use by teenagers is to treat them like adults. Rather than simply tell them to “Just Say No” to alcohol, tobacco or illicit drugs, it may be more helpful to explain how these substances create unique risks for them risks that arise due to the changing state of […]

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Teen Brain Volume Changes With Small Amount of Cannabis Use, Study Finds

Just one or two joints seem to change the structure of the brain, say researchers from universities around the world, led by senior author and University of Vermont professor of psychiatry Hugh Garavan, PhD, and first author and former UVM postdoctoral fellow Catherine Orr, PhD.   The study is part of a long-term European effort […]

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Paternal Δ9-Tetrahydrocannabinol Exposure Prior To Mating Elicits Deficits In Cholinergic Synaptic Function In The Offspring

Abstract Little attention has been paid to the potential impact of paternal marijuana use on offspring brain development. We administered Δ9-tetrahydrocannabinol (THC, 0, 2, or 4 mg/kg/day) to male rats for 28 days. Two days after the last THC treatment, the males were mated to drug-naïve females. We then assessed the impact on development of acetylcholine (ACh) […]

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New Drug On Montreal’s Streets Even More Potent Than Fentanyl

A new report from Montreal public health indicates a new drug that’s stronger than fentanyl has hit the city’s streets. MONTREAL — A new drug that is even more powerful than fentanyl is circulating on Montreal’s streets, according to public health officials. Isotonitazene, a chemically manufactured opioid, has killed at least one person in Montreal. […]

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Dem gov recriminalizes drug possession despite voter referendum after overdose deaths, crime surge in Oregon

By  Ryan King. Published April 2, 2024. The high times are over in Oregon. Democratic Gov. Tina Kotek signed legislation Monday to recriminalize the possession of small amounts of certain drugs as the state grapples with a major overdose crisis, ending a legalization experiment backed by voters four years ago. The new law makes keeping drugs such as heroin […]

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Teen Drug Use Habits Are Changing, For the Good. With Caveats.

A CONVERSATION WITH … Dr. Nora Volkow, who leads the National Institutes of Drug Abuse, would like the public to know things are getting better. Mostly. Volkov says:  “People don’t really realize that among young people, particularly teenagers, the rate of drug use is at the lowest risk that we have seen in decades,”  By Matt […]

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Women who use marijuana during pregnancy are nearly TWICE as likely to give birth to a child with autism, study suggests

Neither the cause of autism nor the effects of cannabis on a developing fetus are entirely clear  Researchers at the Ottawa Hospital and University of Ottawa studied 2,200 Canadian women who reported using marijuana while pregnant  The rate of autism among their children was four per 1,000 person-years, compared to 2.42 among children whose mothers […]

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Cannabis In Pregnancy – Rejoinder, Exposition And Cautionary Tales

Cannabis use during pregnancy is associated with a host of negative outcomes. Sondem/AdobeStock The recent paper by Stanciu discussing cannabis use in pregnancy1 makes several useful and highly salient points. With a more complete understanding of the published literature further important patterns in the data emerge. They aid our understanding of the pathobiology of in utero cannabis exposure and thereby […]

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Novel Insights On Cannabis And Psychosis

There is evidence in both patients with psychotic disorders and the general population that cannabis use is associated with adverse effects of psychopathology and cognition. RESEARCH UPDATE Substance use comorbidity in schizophrenia has been described as “the rule rather than the exception.”1 The large Epidemiological Catchment Area study estimated that 47% of patients with schizophrenia also had a […]

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Do You Have the Heart for Marijuana?

Research suggests that smoking marijuana carries many of the same cardiovascular health hazards as smoking tobacco. Credit…Gracia Lam Do you have the heart to safely smoke pot? Maybe not, a growing body of medical reports suggests. Currently, increased smoking of marijuana in public, even in cities like New York where recreational use remains illegal (though […]

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Paediatric Cannabis Poisonings In France: More And More Frequent And Severe

Abstract Accidental paediatric cannabis poisonings are an incidental effect of cannabis use. The average THC content of cannabis resin and the number of consumers are rising sharply in the USA and in most European countries. The objective is to study the evolution of prevalence and severity of paediatric exposures to cannabis in France. Method This […]

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Study Finds Link Between Prenatal THC Exposure And Autism

A new study recently published in Nature Medicine found a stunning association between prenatal THC exposure and development of autism. Using provincial birth registries, Canadian researchers analyzed all live births that occurred in Ontario between April 2007 and March 2012 for a total of 497,821 births. Investigators found that infants who were prenatally exposed to THC were […]

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School substance use prevention efforts are crucial. The question is how to do it.

Side Effects Public Media | By Alex Li Published March 13, 2024 at 1:49 PM EDT In 2021, fentanyl was identified in more than three-quarters of adolescent overdose deaths, but experts say schools are slow to adapt their prevention efforts. Alex Li was a health reporter with Side Effects Public Media based at WFYI in Indianapolis, Ind. […]

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Smoking Now Fuels More Drug Overdoses than Injecting Does

Despite stereotypical images of addicts injecting heroin and then dying, new government research finds that smoking drugs such as fentanyl is now the leading cause of fatal overdoses. In the new research, published Thursday in Morbidity and Mortality Weekly Report, scientists from the U.S. Centers for Disease Control and Prevention found the percentage of overdose deaths between […]

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Cannabis Use Is Associated With Potentially Heritable Widespread Changes In Autism Candidate Gene DLGAP2 DNA Methylation In Sperm

ABSTRACT Parental cannabis use has been associated with adverse neurodevelopmental outcomes in offspring, but how such phenotypes are transmitted is largely unknown. Using reduced representation bisulphite sequencing (RRBS), we recently demonstrated that cannabis use is associated with widespread DNA methylation changes in human and rat sperm. Discs-Large Associated Protein 2 (DLGAP2), involved in synapse organization, […]

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Drug Free Australia – Introduction – Cutting Edge Research on Cannabis Harms

To Whom it may concern On behalf of Drug Free Australia and our coalition of drug prevention researchers, we wish to commend to you, research that could well be a game-changer in informing and preventing a large proportion of Australia’s substance use issues. The research is in various stages of development and a synopsis of […]

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Cannabis Use During Adolescence And The Occurrence Of Depression, Suicidality And Anxiety Disorder Across Adulthood: Findings From A Longitudinal Cohort Study Over 30 Years

Highlights Population-based longitudinal cohort study over 30 years spanning age 19/20 to 49/50 Cannabis use in adolescence predicted the occurrence of depression and suicidality in adulthood Association between adolescent cannabis use and adult depression/suicidality hold when adjusted for various covariates, including time-varying pattern of substance abuse in adulthood Younger age at first cannabis use and more […]

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Drug Dealers: Dealing with Drugs and Dealers

The sale and use of illegal drugs are among the most serious problems facing the UK, indeed, the entire world, right now. This issue is particularly prevalent within Britain’s night-time economy, where even the most stringently law-abiding and responsibly run premises are not guaranteed to be completely free from the presence of drugs and/or drug dealers. […]

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20 REASONS TO VOTE NO TO LEGALIZING CANNABIS – NEW ZEALAND

Source: 20-Reasons-to-Vote-NO-in-2020-SAM-VERSION-Cannabis.pdf (saynopetodope.org.nz) May 2020

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Review Of Studies Suggests THC In Cannabis Could Induce Psychiatric Symptoms In Healthy People

In what is sure to be a controversial finding among cannabis users and proponents, a review of existing research published this week in The Lancet Psychiatry suggests that a single dose of THC may induce a variety of psychiatric symptoms associated with schizophrenia and other psychiatric disorders. According to a news release issued by The Lancet on March 17: A single dose of […]

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Cannabis Exposure As An Interactive Cardiovascular Risk Factor And Accelerant Of Organismal Ageing: A Longitudinal Study

Abstract Objectives: Many reports exist of the cardiovascular toxicity of smoked cannabis but none of arterial stiffness measures or vascular age (VA). In view of its diverse toxicology, the possibility that cannabis-exposed patients may be ageing more quickly requires investigation. Design: Cross-sectional and longitudinal, observational. Prospective. Setting: Single primary care addiction clinic in Brisbane, Australia. Participants: 11 cannabis-only smokers, […]

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A Synopsis Of The Numerous Studies Supporting An Causal Relationship Between Marijuana Use And The Chronic Psychotic Disorder Schizophrenia

A meta-analysis of all studies worldwide showing association between marijuana use and schizophrenia: Moore TH, Zammit S, Lingford-Hughes A, et al. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 2007;370:319–328. http://dirwww.colorado.edu/alcohol/downloads/Cannabis_and_behavior.pdf “There was an increased risk of any psychotic outcome in individuals who had ever used cannabis…with greater […]

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A Novel Phytocannabinoid Isolated From Cannabis sativa L. With An In Vivo Cannabimimetic Activity Higher Than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol

(-)-Trans-Δ9-tetrahydrocannabinol (Δ9-THC) is the main compound responsible for the intoxicant activity of Cannabis sativa L. The length of the side alkyl chain influences the biological activity of this cannabinoid. In particular, synthetic analogues of Δ9-THC with a longer side chain have shown cannabimimetic properties far higher than Δ9-THC itself. In the attempt to define the […]

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We Know Vaping Can Cause Serious Lung Problems. A New Study Says It Might Also Cause Cancer

In a study published this week, researchers asked tens of thousands of individuals over 12 years of age about their use of tobacco products, e-cigarettes, and their health, and conducted follow-up questions over three years.1 They found the development of lung problems like emphysema, bronchitis, asthma, and chronic obstructive pulmonary disease in individuals who had […]

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Letter from Pamela McColl

Alex Azar Secretary of Health and Human Services US Department of Health and Human Services 200 Independence Avenue SW Washington D.C, 20201 November 5, 2019 Dear Secretary Azar: This letter is to bring to your attention a study underway at the University of Washington referred to as the “Moms and Marijuana Study” and granted under […]

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U.S. Surgeon General’s Advisory: Marijuana Use And The Developing Brain

I, Surgeon General VADM Jerome Adams, am emphasizing the importance of protecting our Nation from the health risks of marijuana use in adolescence and during pregnancy. Recent increases in access to marijuana and in its potency, along with misperceptions of safety of marijuana endanger our most precious resource, our nation’s youth. BE PREPARED. GET NALOXONE. […]

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Quebec Pot Arrests Behind The Wheel Up 54% Since Legalization

Police forces in the province collected 795 blood samples from motorists suspected of driving while under the influence. One year after the legalization of recreational use of cannabis in Canada, the black market for the drug — as well as its use behind the wheel — continues to keep Quebec police forces busy. In 2018, police collected 795 blood […]

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Drug And Alcohol Use In College-Age Adults in 2018

The 2018 Monitoring the Future College Students and Young Adults survey shows trends in the use of marijuana, alcohol, nicotine, and synthetic drugs in college students and non-college peers.   Marijuana Use Annual Marijuana Use at Historic Highs among College and Non-College Peers* Marijuana use is nearly the same for college students and their non-college […]

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Medical Use Of Cannabis In 2019

Nearly 10% of cannabis users in the United States report using it for medicinal purposes. As of August 2019, 33 states and the District of Columbia have initiated policies allowing the use of cannabis or cannabinoids for the management of specific medical conditions. Yet, the federal government still classifies cannabis as illegal, complicating its medical […]

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Cannabis Hyperemesis Syndrome, Without the Hype

Cannabis hyperemesis syndrome (CHS) is nothing new, but nonetheless lacks a diagnosis code. This means that nobody—including the Centers for Disease Control and Prevention, which is meant to track such things—knows the prevalence of the condition. It is, however, relatively rare. Medical sources say that it’s likely, as you’d expect, to become more common as […]

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He Loved Weed. Then The Vomiting Began. Months Later, He Died

The doctors told Regina Denney and her son Brian Smith Jr. what was causing his severe vomiting and abdominal pain. Neither the teenager nor his mother believed what they said: smoking weed. Smoking marijuana, the two knew, was recommended to cancer patients to spur the appetite. How could it lead to Brian’s condition? As the months went […]

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Fentanyl Hits The Streets Disguised As Xanax And Norco

The rise in prescription opioid and heroin abuse creates countless problems for healthcare professionals, law enforcement, the drug abusers themselves and society as a whole. It’s a complex issue that continues to claim lives. Unfortunately, Fentanyl, a painkiller 100 times more powerful than morphine, is showing up on the streets disguised as other drugs, such as […]

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How Canada Failed To Smash The Cannabis Black Market

30 July 2019 I had forgotten how much I disliked cannabis until I found myself under its influence, in the rain, trying and failing to find Toronto’s Union Train Station so I could get to the airport and go home. The plan had been to enhance my mood for a long journey, floating back to […]

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Examining Brain Health Could Help Fight Methamphetamine Use Disorder   

Methamphetamine, a well-known psychostimulant drugs of abuse is in a resurgence in people using opioids and others. While many treatment options exist for patients with opioid use disorders, alcohol use disorders, and even tobacco smokers, there are far fewer options for people trying to stop using methamphetamines. No known medical treatments exist for overdose, dependence, […]

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If You Smoke Pot, Your Anesthesiologist Needs To Know

Colorado is on the front lines in dealing with how marijuana use affects surgery. Lessons learned on operating tables and in recovery rooms have prompted calls for more research on marijuana nationwide. DENVER — When Colorado legalized marijuana, it became a pioneer in creating new policies to deal with the drug. Now the state’s surgeons, […]

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Uruguay: What have we learned from their experiment? “Not enough”.

INTRODUCTION In 2013, Uruguay became the first country in fully regulating the marijuana market that now operates under state control. In a Washington Post feature article on Uruguay’s cannabis laws, they reported that Uruguay is socially liberal and has a wide separation of church and state. Gambling and prostitution are legal and regulated. Uruguay is also […]

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The Connection Between Stress and Alcoholism

As with any addiction, alcoholism is closely connected with stress. And while plenty of people first started drinking as a way to cope with stress or even just wind down after a long day, developing an alcohol use disorder can end up causing significant stresses of its own. If you’re thinking about pursuing alcohol use disorder treatment for yourself or for a loved […]

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Cannabis in Medicine: An Evidence-Based Approach

The title of “Cannabis in Medicine: An Evidence-Based Approach” contains an irony. In chapter after chapter in this multi-authored book written predominately by providers associated with mainstream medical facilities in Colorado, the authors point out the inadequacy of the evidence we have and the absence of the evidence we need to determine how – or […]

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Cannabis And Pregnancy Don’t Mix

In the September/October 2020 Missouri Medicine, Polocaro and Vettraino raise the important issue of the transgenerational effects of prenatal cannabinoid exposure (PCE) on subsequent generations.1 The implications of multigenerational toxicity of cannabinoids is very far-reaching with major policy implications. The picture presented by Polcaro and Vettraino relating to the mental health implications of PCE is correct if […]

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Time For Safer Injecting Spaces In Britain?

‘Hot topics’ offer background and analysis on important issues which sometimes generate heated debate. Drug consumption rooms are a particularly contentious form of harm reduction, viewed on one hand as a practical, humane, life-saving approach to dangerous drug use, and on the other, as an endorsement of drugtaking and a dereliction of the duty to […]

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Navajo Nation Moves To Shut Down Hemp Farms Amid Claims Of Marijuana Growing

Hemp plants are visible inside several structures on Sept. 16, 2020, in Shiprock, New Mexico. NOEL LYN SMITH/THE FARMINGTON DAILY TIMES USA TODAY NETWORK – NEW MEXICO Leaders on the Navajo Nation have cracked down on one of its members who they say has used immigrant labor to transform 400 acres of crop land into hemp farms in […]

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"When representing a cause (almost) lost, sound your trumpet, mount your steed and go for the very last charge, failing which you will die of sad old age in the depths of the forgotten fortress, no longer besieged because life has abandoned it for greener pastures."

Jean Raspail
From the website of jeanraspail.net

"Universal prevention initiatives are important elements of a comprehensive prevention strategy that should include selective and indicated prevention initiatives as well. In order to prevent the development of dependence you need all three - and you cannot do without universal prevention. Norms, attitudes, availability are important risk factors for developing drug use problems as well as neighbourhood disorganization and weak family bonds."

Christina Gynna, Deputy National Drugs Policy Co-ordinator, Sweden,
at the ICAA conference in Budapest, 24 October 2005

 
 

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