{"id":15482,"date":"2019-07-02T18:53:26","date_gmt":"2019-07-02T18:53:26","guid":{"rendered":"https:\/\/drugprevent.org.uk\/ppp\/?p=15482"},"modified":"2020-01-20T20:07:24","modified_gmt":"2020-01-20T20:07:24","slug":"death-by-self-mutilation-after-oral-cannabis-consumption","status":"publish","type":"post","link":"https:\/\/drugprevent.org.uk\/ppp\/2019\/07\/death-by-self-mutilation-after-oral-cannabis-consumption\/","title":{"rendered":"Death By Self-Mutilation After Oral Cannabis Consumption."},"content":{"rendered":"<p style=\"text-align: justify\"><span style=\"font-family: verdana, geneva, sans-serif;font-size: 10pt;color: #0000ff\">Abstract<\/span><\/p>\n<div class=\"\">\n<p style=\"text-align: justify\"><span style=\"font-family: verdana, geneva, sans-serif;font-size: 10pt;color: #0000ff\">Major self-mutilation (amputation, castration, self-inflicted eye injuries) is frequently associated with psychiatric disorders and\/or substance abuse. A 35-year-old man presented with behavioral disturbances of sudden onset after oral cannabis consumption and major self-mutilation (attempted amputation of the right arm, self-enucleation of both eyes and impalement) which resulted in death. During the enquiry, four fragments of a substance resembling cannabis resin were seized at the victim&#8217;s home. Autopsy confirmed that death was related to hemorrhage following the mutilations. Toxicological findings showed cannabinoids in femoral blood (tetrahydrocannabinol (THC) 13.5\u202fng\/mL, 11-hydroxy-tetrahydrocannabinol (11-OH-THC) 4.1\u202fng\/mL, 11-nor-9-carboxy-THC (THC-COOH) 14.7\u202fng\/mL, cannabidiol (CBD) 1.3\u202fng\/mL, cannabinol (CBN) 0.7\u202fng\/mL). Cannabinoid concentrations in hair (1.5\u202fcm brown hair strand\/1 segment) were consistent with concentrations measured in chronic users (THC 137\u202fpg\/mg, 11-OH-THC 1\u202fpg\/mg, CBD 9\u202fpg\/mg, CBN 94\u202fpg\/mg). Analysis of the fragments seized confirmed that this was cannabis resin with high levels of THC (31-35%). We discuss the implications of oral consumption of cannabis with a very high THC content.<\/span><\/p>\n<p><span style=\"font-family: verdana, geneva, sans-serif;font-size: 10pt;color: #0000ff\">Source: <a style=\"color: #0000ff\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29125965\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29125965<\/a> January 2018<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Abstract Major self-mutilation (amputation, castration, self-inflicted eye injuries) is frequently associated with psychiatric disorders and\/or substance abuse. A 35-year-old man presented with behavioral disturbances of sudden onset after oral cannabis consumption and major self-mutilation (attempted amputation of the right arm, self-enucleation of both eyes and impalement) which resulted in death. During the enquiry, four fragments [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[63,30,32,68],"tags":[],"class_list":["post-15482","post","type-post","status-publish","format-standard","hentry","category-brain-and-behaviour","category-cannabis-marijuana","category-crime-violence-prison","category-drug-use-various-effects"],"_links":{"self":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts\/15482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/comments?post=15482"}],"version-history":[{"count":0,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts\/15482\/revisions"}],"wp:attachment":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/media?parent=15482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/categories?post=15482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/tags?post=15482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}