{"id":19026,"date":"2025-04-26T17:57:15","date_gmt":"2025-04-26T16:57:15","guid":{"rendered":"https:\/\/drugprevent.org.uk\/ppp\/?p=19026"},"modified":"2025-08-10T16:52:11","modified_gmt":"2025-08-10T15:52:11","slug":"exposure-to-maternal-cannabis-use-disorder-and-risk-of-autism-spectrum-disorder-in-offspring-a-data-linkage-cohort-study","status":"publish","type":"post","link":"https:\/\/drugprevent.org.uk\/ppp\/2025\/04\/exposure-to-maternal-cannabis-use-disorder-and-risk-of-autism-spectrum-disorder-in-offspring-a-data-linkage-cohort-study\/","title":{"rendered":"Exposure to maternal cannabis use disorder and risk of autism spectrum disorder in offspring: A data linkage cohort study"},"content":{"rendered":"<p><span style=\"color: #ff6600;\"><strong>This article, reporting on research by Profs Stuart Reece and Gary Hulse, is seen as seminal contribution to the current concerns about the effects of cannabis use on autism. Accordingly, NDPA has written to JF Kennedy Jnr as below:<\/strong><\/span><\/p>\n<p><a href=\"https:\/\/drugprevent.org.uk\/ppp\/2025\/04\/exposure-to-maternal-cannabis-use-disorder-and-risk-of-autism-spectrum-disorder-in-offspring-a-data-linkage-cohort-study\/ndpa-logo-2\/\" rel=\"attachment wp-att-19028\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-19028\" src=\"https:\/\/drugprevent.org.uk\/ppp\/wp-content\/uploads\/2025\/04\/NDPA-logo.jpg\" alt=\"\" width=\"266\" height=\"186\" \/><\/a><\/p>\n<p><span style=\"color: #ff6600;\"><strong>Date: 20th April 2025<\/strong><\/span><\/p>\n<p><span style=\"color: #ff6600;\"><strong>Importance:<\/strong> High<\/span><\/p>\n<p><span style=\"color: #ff6600;\">To Robert F. Kennedy Jnr, Secretary of Health and Human Services, Government of the United States<\/span><\/p>\n<p><span style=\"color: #ff6600;\">Sir,<\/span><\/p>\n<p><span style=\"color: #ff6600;\">I understand that you and President Trump are becoming extremely concerned about the US autism epidemic.<\/span><\/p>\n<p><span style=\"color: #ff6600;\">Please see the attached paper above suggesting that Maternal Cannabis use and CUD may be a factor.<\/span><\/p>\n<p><span style=\"color: #ff6600;\">This paper attached is independently supportive of the other Australian work by Professors Reese and Hulse.<\/span><\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=x8bDLzEInWA&amp;t=935s\">https:\/\/www.youtube.com\/watch?v=x8bDLzEInWA&amp;t=935s<\/a><\/p>\n<p><span style=\"color: #ff6600;\">The Reese\/Hulse work indicates strong concordance between Cannabis legalization States and an those same States having an increase in ASD.<\/span><\/p>\n<p><span style=\"color: #ff6600;\">Yours sincerely,<\/span><\/p>\n<p><span style=\"color: #ff6600;\">David Raynes, Senior Advisor, NDPA (UK)<\/span><\/p>\n<p><span style=\"color: #ff6600;\">UK NATIONAL DRUG PREVENTION ALLIANCE<\/span><\/p>\n<p><span style=\"color: #ff6600;\">+44 7967708568<\/span><\/p>\n<p>&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;&lt;NDPA&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;&gt;<\/p>\n<h2><a href=\"https:\/\/drugprevent.org.uk\/ppp\/2025\/04\/exposure-to-maternal-cannabis-use-disorder-and-risk-of-autism-spectrum-disorder-in-offspring-a-data-linkage-cohort-study\/elsevier\/\" rel=\"attachment wp-att-19031\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-19031\" src=\"https:\/\/drugprevent.org.uk\/ppp\/wp-content\/uploads\/2025\/04\/Elsevier.jpg\" alt=\"\" width=\"238\" height=\"64\" \/><\/a><\/h2>\n<h2 id=\"publication-title\" class=\"publication-title u-h3\"><a class=\"anchor anchor-secondary publication-title-link\" title=\"Go to Psychiatry Research on ScienceDirect\" href=\"https:\/\/www.sciencedirect.com\/journal\/psychiatry-research\"><span class=\"anchor-text-container\"><span class=\"anchor-text\">Psychiatry Research<\/span><\/span><\/a><\/h2>\n<div class=\"text-xs\"><a class=\"anchor anchor-primary\" title=\"Go to table of contents for this volume\/issue\" href=\"https:\/\/www.sciencedirect.com\/journal\/psychiatry-research\/vol\/337\/suppl\/C\"><span class=\"anchor-text-container\"><span class=\"anchor-text\">Volume 337<\/span><\/span><\/a>,\u00a0<span style=\"color: #0000ff;\">July 2024, 115971<\/span><\/div>\n<div><\/div>\n<div><span style=\"text-decoration: underline;\"><span style=\"color: #0000ff;\"><strong>Exposure to maternal cannabis use disorder and risk of autism spectrum disorder in offspring: A data linkage cohort study.<\/strong><\/span><\/span><\/div>\n<p><span class=\"given-name\" style=\"color: #000000; font-family: Arial; font-size: 13.3333px; text-align: center; background-color: #f0f0f0;\">by Abay Woday<\/span><span style=\"color: #000000; font-family: Arial; font-size: 13.3333px; text-align: center; background-color: #f0f0f0;\">\u00a0<\/span><span class=\"text surname\" style=\"color: #000000; font-family: Arial; font-size: 13.3333px; text-align: center; background-color: #f0f0f0;\">T<\/span><span class=\"text surname\" style=\"color: #000000; font-family: Arial; font-size: 13.3333px; text-align: center; background-color: #f0f0f0;\">adesse<\/span><span style=\"color: #000000; font-family: Arial; font-size: 13.3333px; text-align: center; background-color: #f0f0f0;\"> et al.\u00a0 \u00a0 School of Population Health, Curtin University, Kent Street, Bentley, WA, 6102, Australia<\/span><\/p>\n<div id=\"abstracts\" class=\"Abstracts u-font-serif\">\n<div id=\"abs0001\" class=\"abstract author-highlights\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">Highlights<\/h2>\n<div id=\"abss0001\">\n<div id=\"spara001\" class=\"u-margin-s-bottom\">\n<ul class=\"list\">\n<li class=\"react-xocs-list-item\"><span class=\"list-label\">\u2022\u00a0 \u00a0 \u00a0<\/span>This study involved over 222,000 mother-offspring pairs.<\/li>\n<li class=\"react-xocs-list-item\"><span class=\"list-label\">\u2022\u00a0 \u00a0 \u00a0<\/span>Maternal prenatal\u00a0<a class=\"topic-link\" title=\"Learn more about CUD from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/cannabis-use\">CUD<\/a>\u00a0is linked to higher\u00a0<a class=\"topic-link\" title=\"Learn more about ASD from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/pervasive-developmental-disorder\">ASD<\/a>\u00a0risk, with a stronger risk in male offspring.<\/li>\n<li class=\"react-xocs-list-item\"><span class=\"list-label\">\u2022\u00a0 \u00a0 \u00a0<\/span>More research is needed to understand these gender-specific effects.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"abs0002\" class=\"abstract author\">\n<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">Abstract<\/h2>\n<div id=\"abss0002\">\n<div id=\"spara002\" class=\"u-margin-s-bottom\">This study aimed to investigate the association between pre-pregnancy, prenatal and perinatal exposures to cannabis use disorder (CUD) and the risk of autism spectrum disoder (ASD) in offspring. Data were drawn from the New South Wales (NSW) Perinatal Data Collection (PDC), population-based, linked administrative health data encompassing all-live birth cohort from January 2003 to December 2005. This study involved 222 534 mother-offspring pairs. . The exposure variable (CUD) and the outcome of interest (ASD) were identified using the 10th international disease classification criteria, Australian Modified (ICD-10-AM). We found a three-fold increased risk of ASD in the offspring of mothers with maternal CUD compared to non-exposed offspring. In our sensitivity analyses, male offspring have a higher risk of ASD associated with maternal CUD than their female counterparts. In conclusion, exposure to maternal CUD is linked to a higher risk of ASD in offspring, with a stronger risk in male offspring. Further research is needed to understand these gender-specific effects and the relationship between maternal CUD and ASD risk in children.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<p><strong>To access the full document:<\/strong><\/p>\n<p><strong>Click on the \u2018Source\u2019 link below.<\/strong><\/p>\n<p><span style=\"font-size: 14pt;\"><strong>Source: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0165178124002567\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0165178124002567<\/a><\/strong><\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>This article, reporting on research by Profs Stuart Reece and Gary Hulse, is seen as seminal contribution to the current concerns about the effects of cannabis use on autism. Accordingly, NDPA has written to JF Kennedy Jnr as below: Date: 20th April 2025 Importance: High To Robert F. Kennedy Jnr, Secretary of Health and Human [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15,30,68,41,64,60,101,128],"tags":[],"class_list":["post-19026","post","type-post","status-publish","format-standard","hentry","category-australia","category-cannabis-marijuana","category-drug-use-various-effects","category-drug-use-effects-on-foetus","category-health","category-marijuana-and-medicine","category-psychiatric-drugs","category-uk"],"_links":{"self":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts\/19026","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/comments?post=19026"}],"version-history":[{"count":0,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts\/19026\/revisions"}],"wp:attachment":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/media?parent=19026"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/categories?post=19026"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/tags?post=19026"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}