{"id":5147,"date":"2009-10-06T13:57:54","date_gmt":"2009-10-06T12:57:54","guid":{"rendered":"https:\/\/drugprevent.org.uk\/ppp\/?p=5147"},"modified":"2009-10-12T14:56:53","modified_gmt":"2009-10-12T13:56:53","slug":"alcohol-consumption-increases-the-risk-of-acute-myocardial","status":"publish","type":"post","link":"https:\/\/drugprevent.org.uk\/ppp\/2009\/10\/alcohol-consumption-increases-the-risk-of-acute-myocardial\/","title":{"rendered":"Alcohol Consumption Increases the Risk of Acute Myocardial Infarction in the Next 12 Hours"},"content":{"rendered":"

\u00a0<\/span><\/strong><\/p>\n

Regular moderate alcohol consumption may be a protective<\/span><\/p>\n

factor for cardiovascular disease. However, the effect<\/span><\/p>\n

of alcohol consumption immediately prior to cardiovascular<\/span><\/p>\n

events has not been studied extensively. Researchers conducted<\/span><\/p>\n

a \u201ccase-crossover\u201d study in 250 first-time nonfatal<\/span><\/p>\n

acute myocardial infarction (AMI) cases to assess the influence<\/span><\/p>\n

of alcohol consumption in the 12 hours preceding<\/span><\/p>\n

AMI. Each case served as its own control; i.e., the control<\/span><\/p>\n

information for each subject was based on his or her own<\/span><\/p>\n

past behavior. The 12 hours preceding AMI was considered<\/span><\/p>\n

the hazard period, while the corresponding time period a<\/span><\/p>\n

week before AMI was the control period.<\/span><\/p>\n

\u00a0<\/span><\/p>\n

Drinking any alcohol in the hazard period increased<\/span><\/p>\n

the risk for AMI threefold (odds ratio [OR], 3.1); even<\/span><\/p>\n

moderate drinking (U24 g of ethanol for women and<\/span><\/p>\n

U36 g for men) more than doubled it (OR, 2.3).<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/span>Of the 187 subjects who drank any alcohol, 15 men<\/span><\/p>\n

and 2 women reported heavy episodic drinking (4+<\/span><\/p>\n

drinks per occasion for women and 5+ drinks for<\/span><\/p>\n

men). The association between heavy episodic drinking<\/span><\/p>\n

and AMI was not significant (OR, 3.0).<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/span>These results were not influenced by known risk factors<\/span><\/p>\n

for AMI (age, gender, smoking status, family history<\/span><\/p>\n

of AMI, hypertension, hyperlipidemia, diabetes,<\/span><\/p>\n

prior unstable angina pectoris, physical exertion<\/span><\/p>\n

shortly before the event, psychological stress, or cocaine<\/span><\/p>\n

use) in adjusted analyses.<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/span>Compared with an age- and sex-matched general<\/span><\/p>\n

population sample, subjects with AMI had more frequent<\/span><\/p>\n

heavy episodic drinking (less than monthly, 21%<\/span><\/p>\n

versus 11%; monthly or more, 7% versus 3%) and were<\/span><\/p>\n

more likely to drink irregularly, i.e., less than weekly<\/span><\/p>\n

(29% versus 16%).<\/span><\/p>\n

\u00a0<\/span><\/p>\n

Comments<\/span><\/em>: <\/span>Drinking any alcohol increased the risk for AMI in<\/span><\/p>\n

the next 12 hours in this study. Researchers were not able<\/span><\/p>\n

to demonstrate a significant association between heavy episodic<\/span><\/p>\n

drinking and AMI due to the small number of exposed<\/span><\/p>\n

subjects; however, the sample had higher rates of heavy and<\/span><\/p>\n

irregular drinking compared with the general population,<\/span><\/p>\n

giving some support to the hypotheses that heavy drinking<\/span><\/p>\n

increases AMI risk, and that pattern of drinking is important<\/span><\/p>\n

when assessing the risk for cardiovascular events. The relationship<\/span><\/p>\n

between alcohol use and cardiovascular events is<\/span><\/p>\n

likely not as simple as is commonly thought.<\/span><\/p>\n

\u00a0<\/span><\/p>\n

<\/p>\n

Source: <\/em><\/span>Gerlich MG, Kr\u00e4mer A, Gmel G, et al. Patterns<\/span><\/p>\n

<\/span>Gerlich MG, Kr\u00e4mer A, Gmel G, et al. Patterns<\/span><\/em><\/p>\n

of alcohol consumption and acute myocardial infarction: a<\/span><\/p>\n

case-crossover analysis. <\/span>Eur Addict Res. <\/span>2009;15(3):143\u2013149<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u00a0 Regular moderate alcohol consumption may be a protective factor for cardiovascular disease. However, the effect of alcohol consumption immediately prior to cardiovascular events has not been studied extensively. Researchers conducted a \u201ccase-crossover\u201d study in 250 first-time nonfatal acute myocardial infarction (AMI) cases to assess the influence of alcohol consumption in the 12 hours preceding […]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29,68,64],"tags":[],"class_list":["post-5147","post","type-post","status-publish","format-standard","hentry","category-alcohol","category-drug-use-various-effects","category-health"],"_links":{"self":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts\/5147","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/comments?post=5147"}],"version-history":[{"count":0,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/posts\/5147\/revisions"}],"wp:attachment":[{"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/media?parent=5147"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/categories?post=5147"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drugprevent.org.uk\/ppp\/wp-json\/wp\/v2\/tags?post=5147"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}