Highlights
- “Kratom” commonly refers to an herbal substance that can produce opioid- and stimulant-like effects. Kratom and kratom-based products are currently legal and accessible in many areas, though U.S. and international agencies continue to review emerging evidence to inform kratom policy.
- While there are no uses for kratom approved by the U.S. Food and Drug Administration, people report using kratom to manage drug withdrawal symptoms and cravings (especially related to opioid use), pain, fatigue and mental health problems. NIDA supports and conducts research to evaluate potential medicinal uses for kratom and related chemical compounds.
- NIDA also supports research towards better understanding the health and safety effects of kratom use. Rare but serious effects have been reported in people who use kratom, including psychiatric, cardiovascular, gastrointestinal and respiratory problems.
- Compared to deaths from other drugs, a very small number of deaths have been linked to kratom products and nearly all cases involved other drugs or contaminants.
Research topics
To access these references below, go to https://nida.nih.gov/research-topics/kratom#references
What is kratom?
How does kratom affect the body?
How do kratom compounds work in the brain?
How is NIDA advancing research on kratom?
What is the scope of kratom use in the United States?
Why do people use kratom?
Is kratom safe?
How does kratom use affect pregnancy?
Is kratom addictive? Do people experience kratom withdrawal?
How are withdrawal and substance use disorder symptoms related to kratom use treated?
Could kratom be used as medicine?
Is kratom legal?
Find More Resources on Kratom
- Learn more about kratom regulation and safety from the U.S. Food and Drug Administration (FDA).
- Learn more about kratom and its legal status from the Drug Enforcement Administration (DEA).
- Learn more about kratom products marketed as herbal supplements from the National Institutes of Health (NIH) National Center for Complementary and Integrative Health (NCCIH).
Source: https://nida.nih.gov/research-topics/kratom#references